Dengue is a tropical disease caused by the mosquito-borne dengue virus (DENV), a single-stranded RNA virus of the dengue virus (DENV), a single-stranded RNA virus of the Flaviviridae family. The virus spreads between people through bites of Aedes aegypti and Aedes albopictus mosquito species. About half of the world’s population lives in Dengue’s risk areas (tropical and subtropical climates) and Dengue is considered a primary illness in those areas. Dengue infection elicits an immune response in the human body, including the emergence of IgM and IgG antibodies against the virus that can be detected in the blood. Primary infection of Dengue is characterized by elevated levels of IgM antibodies, while high levels of IgG antibodies accompany the secondary infection.